Mary E. Keyes Residence is a co-ed residence that houses up to 280 students across seven floors. Rooms are suite-style, with four people living in each suite. Suites include Kitchenettes with a fridge, cooktop and microwave, and built-in island with stools, living rooms with a love seat, and a coffee table.

There are lounges and study rooms on each floor as well as a large study area and laundry facilities both located on the second floor. Tim Hortons, a convenience store, and “East Meets West Bistro” are all located on the main floor, along with the West Quad Service Centre. This building is served by 2 elevators and is located in the Residence West Quad.